2C-B isn’t used medically because of its current standing as a Schedule I substance in the United States. It’s classified under equivalent filings in other countries, such as the United Kingdom, Canada, Australia, Germany, and Europe. 2C-B is most often used in place of MDMA at concerts, parties, or music festivals. The stimulating and euphoric effects make people feel more social and engaged, it creates a strong sense of empathy and connectedness with other people, and it won’t inhibit your ability to sleep at the end of the night.

It’s important to note, the doses mentioned above were all ingested orally, which is the most popular way to take 2C-B. Folks report either swallowing a pill, weighing out their dose and mixing it with water, or “bombing” their dose by putting it in a rolling paper or piece of toilet paper, and swallowing it all like a pill. But nasal ingestion is also done, although many people warn that it is extremely painful—more so than with other substances. However, if you do choose to ingest nasally, doses should be significantly smaller because it comes on faster and stronger, and will also be shorter-lasting. Combining 2C drugs with other psychedelics can lead to unpredictable effects and may intensify the experience beyond what is expected or desired.

Because the beginning of the high is painful, most people report having an unpleasant experience with the drug. According to the 2019 Global Drug Survey, darknet purchases of the drug significantly increased over 5 years, along with other drugs like DMT and ketamine. Most people take 2C-B orally and experience a burning sensation when ingesting the drug. Occasionally, people snort it, though doing so often causes nosebleeds and is potentially lethal.

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Generally, doses above 15 milligrams can be intense, while ones over 25 – where OEVs become more frequent – are occasionally frightening. Regardless of the prevailing narrative among users, then, 2C-B does come with its negatives. Like MDMA, the drug affects heart rate and the central nervous system, and people occasionally experience headaches after large doses. Watching Mo sweat, it’s also clear that potential for heatstroke exists, so staying well hydrated while raving is essential. 2C-B is a potentially illegal substance, and we do not encourage or condone the use of this substance where it is against the law.

Cardiac risk

Another interesting side effect, or lack thereof, is that many users also report being able to eat and sleep with ease after the experience—something they’ve struggled with after a night with MDMA or LSD. Plus, at low and moderate doses, many report still being able to perform sexually (and really enjoying it), which is pretty famously hard on MDMA without the help of drugs like Viagra. Compared to other psychedelics, 2C-B is considered gentle — which effects described as being a combination of MDMA and LSD.

They treated some 97 clients in total, until the couple’s arrest in 2009. Users will most often orally ingest 2C-B, either in a pill or ‘bomb it’ (wrapping it in a cigarette skin or piece of toilet paper) in powder form. The legal use of 2C-B came to a stop in 1995, when the DEA classed it as a Schedule I substance in the US.

People have also reported profound spiritual and personal experiences during a 2C-B trip, including feelings of connections to the self, others, and the universe, which can last long after the trip has come to an end. Touch, smell, taste, color, and sound all tend to be enhanced during this time, and many people report feeling squarely “in the body”—aware of their muscles and nerves and merging with physical nature. Unlike on MDMA, sexual arousal can be maintained throughout the 2C-B experience. The information we provide is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

Many compounds will change when heated like this, and the byproducts of vaporized 2C-B are not well understood. Additionally, always weigh your dose using a small scale if you’re taking the raw powder. Scales are cheap (less than $20) and could mean the difference between having a positive experience and ending up in a hospital. Other people prefer to fill their own capsules using the raw powder or snorting it (insufflation). Take a lower dose than you normally would and give it time to take effect. In smaller doses these effects are limited, but higher doses of 2C-B produce intense changes in sensory perception.

Legal status

However, we accept that illegal drug use occurs, and believe that offering responsible harm reduction information is imperative to keeping people safe. For that reason, this guide is designed to ensure the safety of those who decide to use the substance. Tolerance to the effects of 2C-B is not built almost immediately after ingestion. 2C-B was first synthesised in 1974 by Alexander Shulgin, and it first saw use among the psychiatric community as an aid during therapy. It was considered one of the best drugs for this purpose because of its short duration, relative absence of side-effects, and comparably mild nature. Shortly after becoming popular in the medical community, it became popular recreationally.

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• Fentanyl is an incredibly powerful and deadly narcotic, with doses as low as two milligrams (a dose so small it could fit on the tip of a pencil) being potentially deadly.
• It is important to note there have been deaths linked to other substances in the 2C family (like 2C-T-7 and 2C-I-NBOMe), and one woman suffered brain injury after ingesting an unknown dose of possibly impure 2C-B.
• Every milligram of 2C-B can affect the experience and so “eyeballing” a dose of powder could get you in deeper than you bargained for, which once happened to Boreta.
• One of the main benefits of 2C-B over MDMA is that users usually don’t experience difficulty falling asleep after the experience.
• Nor is this information, or any journalistic stories, anecdotes, visual or artistic material intended as a replacement or supplement for medical or legal advice.

Remember, everyone’s experience with psychoactive substances is unique, as is the integration process. Be patient and kind to yourself as you go through this journey—safe travels and happy tripping, fellow psychonauts. 2C-B is also likely to interact negatively with other stimulating substances, such as amphetamines (Adderall), MDMA, MDA, cocaine, caffeine, and nicotine. Additionally, the few clinical trials that are available involving 2C-B have all reported the drug had little to no side effects and that the drug had a high level of safety. In this comprehensive guide, we embark on a journey of exploration into the depths of this enigmatic psychedelic compound.

Embarking on a psychedelic journey with 2C-B can be an adventure of sensory enhancement and emotional exploration. One of the most prominent features of a 2C-B trip is the visual spectacle it may present. Users frequently report a vivid intensification of colors, with the world taking on a kaleidoscopic quality.

Fentanyl is an incredibly powerful and deadly narcotic, with doses as low as two milligrams (a dose so small it could 2cb psychedelic fit on the tip of a pencil) being potentially deadly. While it is never recommended to consume any illicit substances, it is critical that you or the people you know test any drugs you may ingest for fentanyl. Several non-profit harm reduction organizations, such as DanceSafe, offer fentanyl testing strips and at-home drug testing kits. Dr. Paloma Lehfeldt, MD, MA, is deeply committed to advancing plant medicine and advocating for the integration of psychedelics into mental health care.

Receptor binding

Physical addiction is differentiated from behavioral addiction in that there is a physical change to the body’s homeostatic default settings in response to the drug. When we take a substance repeatedly, the body makes changes to adapt to the presence of the substance. This is called dependence because we depend on having the drug in our system to maintain balance.

Cognitive effects

• It’s known for enhancing one’s senses and feelings and amplifying visuals, sound, and touch.
• In his book PiHKAL (Phenethylamines I Have Known And Loved), the legendary psychopharmacologist and author Alexander “Sasha” Shulgin named 2C-B one of the six most important phenethylamines for healing trauma.
• Sometimes, bad trips are the result of adulterants (ingredients you weren’t expecting to be in there).
• 2C-B isn’t used medically because of its current standing as a Schedule I substance in the United States.
• DoubleBlind is a trusted resource for news, evidence-based education, and reporting on psychedelics.

After MDMA became a Schedule I substance in the US, many people migrated to the use of 2C-B, which was relatively unknown by the DEA at the time. It was packaged and sold in sex shops, head shops, and some nightclubs from the mid-’80s to the early ’90s. Whilst it was primarily used for partying, these establishments advertised that “it would alleviate impotence, frigidity and diminished libido”.

By 1995, 2C-B was criminalized and placed in Schedule 1 of the Controlled Substances Act, and the US successfully urged other countries to do the same. However, 2C-B, like all psychedelics, can offer the potential for challenging moments. One’s mindset and environment can influence the experience, so it’s crucial to ensure a comfortable setting and to be with trusted individuals, preferably not alone.

2C-B is not inherently addictive — however, people can form addictions to any mind-altering substance, including 2C-B. It’s wise to avoid any other substances while taking 2C-B to avoid negative interactions. The more 2C-B you take, the further the experience diverges from MDMA. High doses are very psychedelic and can make being at public events very uncomfortable — unlike MDMA.

You can do so using a Marquis Reagent Test Kit; 2C-B is the only substance known to turn the reagent a bright greenish-yellow color according to The Third Wave. 2C-E, like many psychedelics, can have both positive and negative effects. On the positive side, many users have reported transformative experiences, leading to personal growth, enhanced creativity, and a renewed sense of purpose.